Monday, March 5, 2012

Self-rated health and symptomatic knee osteoarthritis over three years: Data from the osteoarthritis initiative

Abstract

Objective:

To determine if a previously published model of the influence of self-rated health on physical, mental and social health among patients with joint replacement surgery could be generalized to persons with symptomatic knee OA. Our second purpose was to determine if self-rated health mediated changes in physical, mental and social health.

Methods:

Persons with symptomatic knee OA (n = 1,127) who participated in the Osteoarthritis Initiative completed the required measures at baseline, 1-, 2-, and 3-year intervals. The key variable of interest was a single-item self-rated health measure. In addition, measures of physical, mental and social health and a set of covariate measures over the 3-year period were analyzed. Structural equation modeling was used to test interrelationships among variables as well as predictive and mediational relationships among self-rated health and mental, physical and social health after adjusting for baseline covariates.

Results:

The full model demonstrated good statistical fit. Prior self-rated health consistently predicted current mental health and social health. Prior social health predicted current self-rated health. Self-rated health also mediated changes in mental health and social health. Only social health changes were mediated by self-rated health over all time periods.

Conclusion:

Self-rated health predicts a variety of outcomes of symptomatic knee OA. In addition, self-rated health mediates changes in social health and mental health. The use of self-rated health as a simple and efficient clinical assessment has potential for clinical utility because of its predictive capability and association with multiple health domains. © 2012 by the American College of Rheumatology

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