Design of Monitoring and Sensor Systems for Bioprocesses by Biomechatronic Methodology

Abstract

Biomechatronic design methodology is discussed for the design of monitoring and sensor systems for biotechnological processes. The bioprocess monitoring systems are examples of complex biomechatronic systems between electronic, mechanical, and biological subsystems, and where in particular the biological parts, through active microbial or cellular components, influence the design solutions in a complex manner. The biomechatronic approach facilitates configuration of the monitoring and sensor systems with production and quality needs in focus, and can by that lead to more efficient design solutions.

Principle and applications of the biomechatronic design methodology are discussed for the design of monitoring and sensor systems for biotechnological processes in order to meet the process economical and regulatory requirements on the manufacturing process and by systematically considering and ranking analytical alternatives commercially available, thereby leading to more efficient design solutions.